Mutations in Envelope gp120 Can Impact Proteolytic Processing of the gp160 Precursor and Thereby Affect Neutralization Sensitivity of Human Immunodeficiency Virus Type 1 Pseudoviruses

The design of an efficient human immunodeficiency virus (HIV) immunogen able to generate broad neutralizing antibodies (NAbs) remains an elusive goal. As more data emerge, it is becoming apparent that one important aspect of such an immunogen will be the proper representation of the envelope protein...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Blay, Wendy M., Kasprzyk, Theresa, Misher, Lynda, Richardson, Barbra A., Haigwood, Nancy L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2007
Gaiak:
Pathogenesis and Immunity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169095/
https://ncbi.nlm.nih.gov/pubmed/17855534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01215-07
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