Human Immunodeficiency Virus-Specific CD8(+) T-Cell Activity Is Detectable from Birth in the Majority of In Utero-Infected Infants

Human immunodeficiency virus (HIV)-infected infants in sub-Saharan Africa typically progress to AIDS or death by 2 years of life in the absence of antiretroviral therapy. This rapid progression to HIV disease has been related to immaturity of the adaptive immune response in infants. We screened 740...

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Autors principals: Thobakgale, Christina F., Ramduth, Dhanwanthie, Reddy, Sharon, Mkhwanazi, Nompumelelo, de Pierres, Chantal, Moodley, Eshia, Mphatswe, Wendy, Blanckenberg, Natasha, Cengimbo, Ayanda, Prendergast, Andrew, Tudor-Williams, Gareth, Dong, Krista, Jeena, Prakash, Kindra, Gupreet, Bobat, Raziya, Coovadia, Hoosen, Kiepiela, Photini, Walker, Bruce D., Goulder, Philip J. R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169079/
https://ncbi.nlm.nih.gov/pubmed/17881456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00624-07
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