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Heme Levels Switch the Function of Hap1 of Saccharomyces cerevisiae between Transcriptional Activator and Transcriptional Repressor

Changes in oxygen levels cause widespread changes in gene expression in organisms ranging from bacteria to humans. In Saccharomyces cerevisiae, this response is mediated in part by Hap1, originally identified as a heme-dependent transcriptional activator that functions during aerobic growth. We show...

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Bibliografiske detaljer
Main Authors: Hickman, Mark J., Winston, Fred
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169065/
https://ncbi.nlm.nih.gov/pubmed/17785431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00887-07
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