Type I Interferon Production during Herpes Simplex Virus Infection Is Controlled by Cell-Type-Specific Viral Recognition through Toll-Like Receptor 9, the Mitochondrial Antiviral Signaling Protein Pathway, and Novel Recognition Systems

Recognition of viruses by germ line-encoded pattern recognition receptors of the innate immune system is essential for rapid production of type I interferon (IFN) and early antiviral defense. We investigated the mechanisms of viral recognition governing production of type I IFN during herpes simplex...

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Bibliographische Detailangaben
Hauptverfasser: Rasmussen, Simon B., Sørensen, Louise N., Malmgaard, Lene, Ank, Nina, Baines, Joel D., Chen, Zhijian J., Paludan, Søren R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Cellular Response to Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168887/
https://ncbi.nlm.nih.gov/pubmed/17913820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01167-07
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