Protective Immunity to Pseudomonas aeruginosa Induced with a Capsid-Modified Adenovirus Expressing P. aeruginosa OprF

This study focuses on the development of a new clinical vaccine candidate (AdOprF.RGD.Epi8) against Pseudomonas aeruginosa using an E1(−) E3(−) adenovirus (Ad) vector expressing OprF (AdOprF.RGD.Epi8) and modifications of the Ad genome providing two capsid changes: (i) modification of the Ad hexon g...

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Bibliografske podrobnosti
Main Authors: Worgall, Stefan, Krause, Anja, Qiu, JianPing, Joh, Ju, Hackett, Neil R., Crystal, Ronald G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168865/
https://ncbi.nlm.nih.gov/pubmed/17942539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01246-07
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