Altered Pathogenesis of Porcine Respiratory Coronavirus in Pigs due to Immunosuppressive Effects of Dexamethasone: Implications for Corticosteroid Use in Treatment of Severe Acute Respiratory Syndrome Coronavirus

The pathogenesis and optimal treatments for severe acute respiratory syndrome (SARS) are unclear, although corticosteroids were used to reduce lung and systemic inflammation. Because the pulmonary pathology of porcine respiratory coronavirus (PRCV) in pigs resembles SARS, we used PRCV as a model to...

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Detalhes bibliográficos
Main Authors: Jung, Kwonil, Alekseev, Konstantin P., Zhang, Xinsheng, Cheon, Doo-Sung, Vlasova, Anastasia N., Saif, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168842/
https://ncbi.nlm.nih.gov/pubmed/17942563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01702-07
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