A High Viral Burden Predicts the Loss of CD8 T-Cell Responses Specific for Subdominant Gag Epitopes during Chronic Human Immunodeficiency Virus Infection

Human immunodeficiency virus (HIV)-specific CD8 T-cell responses targeting products encoded within the Gag open reading frame have frequently been associated with better viral control and disease outcome during the chronic phase of HIV infection. To further clarify this relationship, we have studied...

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Autori principali: Geldmacher, Christof, Gray, Clive, Nason, Martha, Currier, Jeffrey R., Haule, Antelmo, Njovu, Lilian, Geis, Steffen, Hoffmann, Oliver, Maboko, Leonard, Meyerhans, Andreas, Cox, Josephine, Hoelscher, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168820/
https://ncbi.nlm.nih.gov/pubmed/17898052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01566-07
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