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The Alanine Racemase of Mycobacterium smegmatis Is Essential for Growth in the Absence of d-Alanine

Alanine racemase, encoded by the gene alr, is an important enzyme in the synthesis of d-alanine for peptidoglycan biosynthesis. Strains of Mycobacterium smegmatis with a deletion mutation of the alr gene were found to require d-alanine for growth in both rich and minimal media. This indicates that a...

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Détails bibliographiques
Auteurs principaux: Milligan, Daniel L., Tran, Sieu L., Strych, Ulrich, Cook, Gregory M., Krause, Kurt L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168708/
https://ncbi.nlm.nih.gov/pubmed/17827284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01201-07
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