HIV-1 Tat binds TAF(II)250 and represses TAF(II)250-dependent transcription of major histocompatibility class I genes

HIV Tat, a transactivator of viral transcription, represses transcription of major histocompatibility (MHC) class I genes. Repression depends exclusively on the C-terminal domain of Tat, although the mechanism of this repression has not been known. We now show that repression results from the intera...

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Autors principals: Weissman, Jocelyn D., Brown, Julie A., Howcroft, T. Kevin, Hwang, Jae, Chawla, Ashish, Roche, Paul A., Schiltz, Louis, Nakatani, Yoshihiro, Singer, Dinah S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1998
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21687/
https://ncbi.nlm.nih.gov/pubmed/9751712
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