Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

The mammalian AML/CBFα runt domain (RD) transcription factors regulate hematopoiesis and osteoblast differentiation. Like their Drosophila counterparts, most mammalian RD proteins terminate in a common pentapeptide, VWRPY, which serves to recruit the corepressor Groucho (Gro). Using a yeast two-hybr...

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Bibliografiska uppgifter
Huvudupphovsmän: Levanon, Ditsa, Goldstein, Robert E., Bernstein, Yael, Tang, Hua, Goldenberg, Dalia, Stifani, Stefano, Paroush, Ze’ev, Groner, Yoram
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 1998
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC21685/
https://ncbi.nlm.nih.gov/pubmed/9751710
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