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Cwp84, a Surface-Associated Protein of Clostridium difficile, Is a Cysteine Protease with Degrading Activity on Extracellular Matrix Proteins

Clostridium difficile pathogenicity is mediated mainly by its A and B toxins, but the colonization process is thought to be a necessary preliminary step in the course of infection. The aim of this study was to characterize the Cwp84 protease of C. difficile, which is highly immunogenic in patients w...

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Autors principals: Janoir, Claire, Péchiné, Séverine, Grosdidier, Charlotte, Collignon, Anne
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168428/
https://ncbi.nlm.nih.gov/pubmed/17693508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00578-07
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