Use of Synthetic Derivatives To Determine the Minimal Active Structure of Cytokine-Inducing Lipoteichoic Acid

Lipoteichoic acid (LTA) from gram-positive bacteria is the counterpart to lipopolysaccharide from gram-negative bacteria. LTA, which activates Toll-like receptor 2 (TLR2), induces a unique cytokine and chemokine pattern. The chemical synthesis of LTA proved its immunostimulatory properties. To deter...

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Autors principals: Deininger, Susanne, Figueroa-Perez, Ignacio, Sigel, Stefanie, Stadelmaier, Andreas, Schmidt, Richard R., Hartung, Thomas, von Aulock, Sonja
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
Matèries:
Cellular Immunology, Antibodies, and Mediators of Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168384/
https://ncbi.nlm.nih.gov/pubmed/17928431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00007-07
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