Gamma Interferon-Independent Effects of Interleukin-12 on Immunity to Salmonella enterica Serovar Typhimurium

Interleukin-12 (IL-12) and IL-18 are both central to the induction of gamma interferon (IFN-γ), and various roles for IL-12 and IL-18 in control of intracellular microbial infections have been demonstrated. We used IL-12p40(−/−) and IL-18(−/−) mice to further investigate the role of IL-12 and IL-18...

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Main Authors: Price, Jason D., Simpfendorfer, Kim R., Mantena, Radhakrishnam R., Holden, James, Heath, William R., van Rooijen, Nico, Strugnell, Richard A., Wijburg, Odilia L. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168367/
https://ncbi.nlm.nih.gov/pubmed/17875635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00971-07
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