High-Affinity Zn(2+) Uptake System ZnuABC Is Required for Bacterial Zinc Homeostasis in Intracellular Environments and Contributes to the Virulence of Salmonella enterica

To investigate the relevance of zinc in host-pathogen interactions, we have constructed Salmonella enterica mutant strains in which the znuA gene, which encodes the periplasmic component of the ZnuABC high-affinity Zn(2+) transporter, was deleted. This mutation does not alter the ability of Salmonel...

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Main Authors: Ammendola, Serena, Pasquali, Paolo, Pistoia, Claudia, Petrucci, Paola, Petrarca, Patrizia, Rotilio, Giuseppe, Battistoni, Andrea
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2007
נושאים:
Molecular Pathogenesis
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168356/
https://ncbi.nlm.nih.gov/pubmed/17923515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00559-07
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