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PspA and PspC Minimize Immune Adherence and Transfer of Pneumococci from Erythrocytes to Macrophages through Their Effects on Complement Activation

Pneumococcal surface protein A (PspA) and PspC are important virulence factors. Their absence has been shown to allow improved clearance of pneumococci from the blood of mice and to decrease pneumococcal virulence. In the presence of antibody and complement, pneumococci attach to erythrocytes in a p...

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Bibliografski detalji
Glavni autori: Li, Jie, Glover, David T., Szalai, Alexander J., Hollingshead, Susan K., Briles, David E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168335/
https://ncbi.nlm.nih.gov/pubmed/17923519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00839-07
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