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Listeriolysin O Secreted by Listeria monocytogenes into the Host Cell Cytosol Is Degraded by the N-End Rule Pathway

The intracellular pathogen Listeria monocytogenes escapes from a phagosomal compartment into the cytosol by secreting the pore-forming cytolysin listeriolysin O (LLO). During the proliferation of L. monocytogenes bacteria in the mammalian cell cytosol, the secreted LLO is targeted for degradation by...

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Detalles Bibliográficos
Autores principales: Schnupf, Pamela, Zhou, Jianmin, Varshavsky, Alexander, Portnoy, Daniel A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168281/
https://ncbi.nlm.nih.gov/pubmed/17682039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00164-07
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