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Improved Succinic Acid Production in the Anaerobic Culture of an Escherichia coli pflB ldhA Double Mutant as a Result of Enhanced Anaplerotic Activities in the Preceding Aerobic Culture

Escherichia coli NZN111 is a pflB ldhA double mutant which loses its ability to ferment glucose anaerobically due to redox imbalance. In this study, two-stage culture of NZN111 was carried out for succinic acid production. It was found that when NZN111 was aerobically cultured on acetate, it regaine...

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Detalhes bibliográficos
Main Authors: Wu, Hui, Li, Zhi-min, Zhou, Li, Ye, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168152/
https://ncbi.nlm.nih.gov/pubmed/17951436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01546-07
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