Antigenic Polymorphism and Naturally Acquired Antibodies to Plasmodium vivax Merozoite Surface Protein 1 in Rural Amazonians

Merozoite surface protein 1 of Plasmodium vivax (PvMSP-1), a major target for malaria vaccine development, contains six highly polymorphic domains interspersed with conserved sequences. Although there is evidence that the sequence divergence in PvMSP-1 has been maintained over 5 million years by bal...

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Autori principali: Bastos, Melissa S., da Silva-Nunes, Mônica, Malafronte, Rosely S., Hoffmann, Erika Hellena E., Wunderlich, Gerhard, Moraes, Sandra L., Ferreira, Marcelo U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
Soggetti:
Microbial Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168105/
https://ncbi.nlm.nih.gov/pubmed/17699838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00243-07
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