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Expression of Mycoplasma Proteins Carrying an Affinity Tag in M. pneumoniae Allows Rapid Purification and Circumvents Problems Related to the Aberrant Genetic Code

In Mycoplasma pneumoniae and several other mollicutes, the UGA opal codon specifies tryptophan rather than a translation stop. This often makes it difficult to express Mycoplasma proteins in heterologous hosts. In this work, we demonstrate that mollicute proteins can be fused to an affinity tag and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schmidl, Sebastian R., Hames, Claudine, Stülke, Jörg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168039/
https://ncbi.nlm.nih.gov/pubmed/17933931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01861-07
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