Novel Plasmid-Mediated 16S rRNA m(1)A1408 Methyltransferase, NpmA, Found in a Clinically Isolated Escherichia coli Strain Resistant to Structurally Diverse Aminoglycosides

We have isolated a multiple-aminoglycoside-resistant Escherichia coli strain, strain ARS3, and have been the first to identify a novel plasmid-mediated 16S rRNA methyltransferase, NpmA. This new enzyme shared a relatively low level of identity (30%) to the chromosomally encoded 16S rRNA methyltransf...

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Detalhes bibliográficos
Main Authors: Wachino, Jun-ichi, Shibayama, Keigo, Kurokawa, Hiroshi, Kimura, Kouji, Yamane, Kunikazu, Suzuki, Satowa, Shibata, Naohiro, Ike, Yasuyoshi, Arakawa, Yoshichika
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168023/
https://ncbi.nlm.nih.gov/pubmed/17875999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00926-07
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