Drugs Designed To Inhibit Human p38 Mitogen-Activated Protein Kinase Activation Treat Toxoplasma gondii and Encephalitozoon cuniculi Infection

We recently showed that the pyridinylimidazoles SB203580 and SB202190, drugs designed to block human p38 mitogen-activated protein kinase (MAPK) activation, also inhibited replication of the medically important intracellular parasite Toxoplasma gondii in cultured human fibroblasts through a direct e...

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Bibliographische Detailangaben
Hauptverfasser: Wei, Shuang, Daniel, Benjamin J., Brumlik, Michael J., Burow, Matthew E., Zou, Weiping, Khan, Imtiaz A., Wadsworth, Scott, Siekierka, John, Curiel, Tyler J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Susceptibility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168015/
https://ncbi.nlm.nih.gov/pubmed/17923491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00680-07
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