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Frequency of Development and Associated Physiological Cost of Azithromycin Resistance in Chlamydia psittaci 6BC and C. trachomatis L2

Azithromycin is a major drug used in the treatment and prophylaxis of chlamydial infections. Spontaneous azithromycin-resistant mutants of Chlamydia psittaci 6BC were isolated in vitro in the plaque assay at a frequency of about 10(−8). Isogenic clonal variants with A(2058)C, A(2059)G, or A(2059)C m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Binet, Rachel, Maurelli, Anthony T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167982/
https://ncbi.nlm.nih.gov/pubmed/17908942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00962-07
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