Antileishmanial Structure-Activity Relationships of Synthetic Phospholipids: In Vitro and In Vivo Activities of Selected Derivatives

Antileishmanial activities of 91 synthetic phospholipids against Leishmania donovani were evaluated in vitro and cytotoxicity assessed against two mammalian cell lines. Promising compounds were tested further in vivo. In vitro structure-activity relationships showed a positive contribution of head g...

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Autores principales: Seifert, Karin, Lemke, Andreas, Croft, Simon L., Kayser, Oliver
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2007
Materias:
Susceptibility
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167978/
https://ncbi.nlm.nih.gov/pubmed/17908944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00465-07
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