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Antileishmanial Structure-Activity Relationships of Synthetic Phospholipids: In Vitro and In Vivo Activities of Selected Derivatives

Antileishmanial activities of 91 synthetic phospholipids against Leishmania donovani were evaluated in vitro and cytotoxicity assessed against two mammalian cell lines. Promising compounds were tested further in vivo. In vitro structure-activity relationships showed a positive contribution of head g...

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書誌詳細
主要な著者: Seifert, Karin, Lemke, Andreas, Croft, Simon L., Kayser, Oliver
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167978/
https://ncbi.nlm.nih.gov/pubmed/17908944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00465-07
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