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Powerful mutator activity of the polA1 mutation within the histidine region of Escherichia coli K-12.

We examined 122 spontaneous histidine auxotrophs accumulated in overnight cultures of polA1 strains of Escherichia coli K-12 at approximate frequencies of 10(-3). One hundred and thirteen appeared to be minus frameshifts, and nine appeared to be deletions. Of the frameshift mutations, 109 affected t...

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Main Authors: Savić, D J, Romac, S P
格式: Artigo
語言:Inglês
出版: 1982
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC216483/
https://ncbi.nlm.nih.gov/pubmed/7037745
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