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Powerful mutator activity of the polA1 mutation within the histidine region of Escherichia coli K-12.

We examined 122 spontaneous histidine auxotrophs accumulated in overnight cultures of polA1 strains of Escherichia coli K-12 at approximate frequencies of 10(-3). One hundred and thirteen appeared to be minus frameshifts, and nine appeared to be deletions. Of the frameshift mutations, 109 affected t...

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Detalles Bibliográficos
Main Authors: Savić, D J, Romac, S P
Formato: Artigo
Idioma:Inglês
Publicado: 1982
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC216483/
https://ncbi.nlm.nih.gov/pubmed/7037745
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