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Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice.

A double mutant of Cryptococcus neoformans which lacked the ability to produce melanin (Mel-) on media containing diphenols and failed to grow at 37 degrees C (temperature sensitive, Tem-) was obtained by UV irradiation and subsequent cloning. The mutant showed two lesions in melanogenesis in that i...

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Autors principals: Kwon-Chung, K J, Polacheck, I, Popkin, T J
Format: Artigo
Idioma:Inglês
Publicat: 1982
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC216368/
https://ncbi.nlm.nih.gov/pubmed/6804444
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