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Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice.

A double mutant of Cryptococcus neoformans which lacked the ability to produce melanin (Mel-) on media containing diphenols and failed to grow at 37 degrees C (temperature sensitive, Tem-) was obtained by UV irradiation and subsequent cloning. The mutant showed two lesions in melanogenesis in that i...

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Publicado en:J Bacteriol
Autores principales: Kwon-Chung, K J, Polacheck, I, Popkin, T J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1982
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC216368/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6804444/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.150.3.1414-1421.1982
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