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Blocking ligand occupancy of the αVβ3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

Blocking αVβ3 integrin occupancy results in attenuation of the cellular migration response to insulin-like growth factor I (IGF-I). To determine whether integrin antagonists alter other IGF-I-stimulated biologic actions, quiescent smooth muscle cells (SMCs) were exposed to echistatin and their abili...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Zheng, Bo, Clemmons, David R.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21622/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.19.11217
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