Proton Transport through Influenza A Virus M2 Protein Reconstituted in Vesicles

Influenza A virus M2 protein is known to form acid-activated, proton-selective, amantadine-sensitive channels. We directly measured proton uptake in vesicles containing reconstituted M2 by monitoring external pH after addition of valinomycin to vesicles with 100-fold-diluted external [K(+)]. Externa...

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Bibliographische Detailangaben
Hauptverfasser: Moffat, J. Craig, Vijayvergiya, Viksita, Gao, Philip F., Cross, Timothy A., Woodbury, Dixon J., Busath, David D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2008
Schlagworte:
Channels, Receptors, and Electrical Signaling
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2157240/
https://ncbi.nlm.nih.gov/pubmed/17827230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.109082
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