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Inhibition of Histone Deacetylase Activity Promotes Invasion of Human Cancer Cells through Activation of Urokinase Plasminogen Activator (uPA)

Histone acetylation plays an important role in chromatin remodeling and gene expression. The molecular mechanisms involved in differential regulation of urokinase plasminogen activator (uPA) gene expression are not fully understood. In this study, we investigated whether histone deacetylation was in...

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Main Authors: Pulukuri, Sai Murali Krishna, Gorantla, Bharathi, Rao, Jasti S.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156646/
https://ncbi.nlm.nih.gov/pubmed/17923479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705867200
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