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N-Glycans Mediate the Apical Sorting of a Gpi-Anchored, Raft-Associated Protein in Madin-Darby Canine Kidney Cells

Glycosyl-phosphatidylinositol (GPI)- anchored proteins are preferentially transported to the apical cell surface of polarized Madin-Darby canine kidney (MDCK) cells. It has been assumed that the GPI anchor itself acts as an apical determinant by its interaction with sphingolipid-cholesterol rafts. W...

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Autors principals: Benting, Jürgen H., Rietveld, Anton G., Simons, Kai
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156177/
https://ncbi.nlm.nih.gov/pubmed/10427087
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