In Vivo, Villin Is Required for Ca(2+)-Dependent F-Actin Disruption in Intestinal Brush Borders

Villin is an actin-binding protein localized in intestinal and kidney brush borders. In vitro, villin has been demonstrated to bundle and sever F-actin in a Ca(2+)-dependent manner. We generated knockout mice to study the role of villin in vivo. In villin-null mice, no noticeable changes were observ...

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Detalhes bibliográficos
Main Authors: Ferrary, Evelyne, Cohen-Tannoudji, Michel, Pehau-Arnaudet, Gérard, Lapillonne, Alexandre, Athman, Rafika, Ruiz, Tereza, Boulouha, Lilia, El Marjou, Fatima, Doye, Anne, Fontaine, Jean-Jacques, Antony, Claude, Babinet, Charles, Louvard, Daniel, Jaisser, Frédéric, Robine, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156144/
https://ncbi.nlm.nih.gov/pubmed/10459016
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