NIM811, a nonimmunosuppressive cyclosporine analogue, suppresses collagen production and enhances collagenase activity in hepatic stellate cells

BACKGROUND/AIMS: A recent decrease in patient survival has been reported among hepatitis C virus (HCV)-infected liver transplant recipients and this may be attributable to progression of fibrosis. We reported previously that cyclosporine suppressed the proliferation of, and collagen production in, h...

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Detalhes bibliográficos
Main Authors: Kohjima, Motoyuki, Enjoji, Munechika, Higuchi, Nobito, Kotoh, Kazuhiro, Kato, Masaki, Takayanagi, Ryoiichi, Nakamuta, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Basic Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156109/
https://ncbi.nlm.nih.gov/pubmed/17919240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2007.01560.x
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