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Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae

The OGG1 gene of Saccharomyces cerevisiae encodes a DNA glycosylase activity that is a functional analog of the Fpg protein from Escherichia coli and excises 7,8-dihydro-8-oxoguanine (8-oxoG) from damaged DNA. The repair of this ubiquitous kind of oxidative damage is essential to prevent mutations b...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Radicella, J. Pablo, Dherin, Claudine, Desmaze, Chantal, Fox, Maurice S., Boiteux, Serge
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21547/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9223305/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.15.8010
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