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A chemical approach to unraveling the biological function of the glycosylphosphatidylinositol anchor

The glycosylphosphatidylinositol (GPI) anchor is a C-terminal posttranslational modification found on many eukaryotic proteins that reside in the outer leaflet of the cell membrane. The complex and diverse structures of GPI anchors suggest a rich spectrum of biological functions, but few have been c...

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Autori principali: Paulick, Margot G., Forstner, Martin B., Groves, Jay T., Bertozzi, Carolyn R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154431/
https://ncbi.nlm.nih.gov/pubmed/18077333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710139104
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