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Determination of Epithelial Na(+) Channel Subunit Stoichiometry from Single-Channel Conductances

The epithelial Na(+) channel (ENaC) is a multimeric membrane protein consisting of three subunits, α, β, and γ. The total number of subunits per functional channel complex has been described variously to follow either a tetrameric arrangement of 2α:1β:1γ or a higher-ordered stoichiometry of 3α:3β:3γ...

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Detalhes bibliográficos
Main Authors: Anantharam, Arun, Palmer, Lawrence G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154365/
https://ncbi.nlm.nih.gov/pubmed/17562820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609716
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