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An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice

The transcription factor GATA-1, which is expressed in several hematopoietic lineages and multipotential progenitors, is required for the development of red blood cells and platelets. To identify control elements of the mouse GATA-1 gene, we analyzed DNase I hypersensitivity of the locus in erythroi...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: McDevitt, Michael A., Fujiwara, Yuko, Shivdasani, Ramesh A., Orkin, Stuart H.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21540/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9223298/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.15.7976
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