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New role for photoreversible pyrimidine dimers in induction of prototrophic mutations in excision-deficient Escherichia coli by UV light.

UV mutagenesis to His+ in certain recA441 lexA51 bacteria was not photoreversible, indicating that pyrimidine dimers are not target lesions. Photoreversibility was observed in recA+ lexA51 bacteria, showing that pyrimidine dimers are needed to activate the recA+ protein (unlike the recA441 protein)...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Ruiz-Rubio, M, Woodgate, R, Bridges, B A, Herrera, G, Blanco, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC215246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3519579/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.166.3.1141-1143.1986
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