Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation

The maturation of dendritic cells (DCs) following exposure to microbial products or inflammatory mediators plays a critical role in initiating the immune response. We now find that maturation can also occur under steady state conditions, triggered by alterations in E-cadherin-mediated DC-DC adhesion...

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Bibliographic Details
Main Authors: Jiang, Aimin, Bloom, Ona, Ono, Satoru, Cui, Weiguo, Unternaehrer, Juli, Jiang, Shan, Whitney, J. Andrew, Connolly, John, Banchereau, Jacques, Mellman, Ira
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151979/
https://ncbi.nlm.nih.gov/pubmed/17936032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.08.015
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