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Effects of Serum on In Vitro Susceptibility Testing of Echinocandins

The effects of protein binding on the activities of caspofungin, anidulafungin, and micafungin were evaluated against Candida and Aspergillus species. Adding human serum sharply increased the MICs of micafungin and anidulafungin and modestly affected the MIC of caspofungin. The increase in MICs does...

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Autores principales: Odabasi, Zekaver, Paetznick, Victor, Rex, John H., Ostrosky-Zeichner, Luis
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151461/
https://ncbi.nlm.nih.gov/pubmed/17785512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01589-06
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