Antiprion Activity of Cholesterol Esterification Modulators: a Comparative Study Using Ex Vivo Sheep Fibroblasts and Lymphocytes and Mouse Neuroblastoma Cell Lines

Our studies on the role of cholesterol homeostasis in the pathogenesis of scrapie revealed abnormal accumulation of cholesterol esters in ex vivo peripheral blood mononuclear cells (PBMCs) and skin fibroblasts from healthy and scrapie-affected sheep carrying a scrapie-susceptible genotype compared t...

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Bibliografske podrobnosti
Main Authors: Pani, Alessandra, Norfo, Claudia, Abete, Claudia, Mulas, Claudia, Putzolu, Marirosa, Laconi, Sergio, Orrù, Christina Doriana, Cannas, M. Dolores, Vascellari, Sarah, La Colla, Paolo, Dessì, Sandra
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151450/
https://ncbi.nlm.nih.gov/pubmed/17709472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00524-07
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