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In Vitro Antimycobacterial Spectrum of a Diarylquinoline ATP Synthase Inhibitor
The diarylquinoline R207910 is in clinical development for tuberculosis treatment. The MIC(50) for 41 drug-susceptible and 44 multidrug-resistant Mycobacterium tuberculosis clinical isolates was 0.032 μg/ml. Out of 20 additional mycobacterial species, three were found to be naturally resistant to R2...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151410/ https://ncbi.nlm.nih.gov/pubmed/17709466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00181-07 |
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