Multidrug resistance protein-mediated transport of chlorambucil and melphalan conjugated to glutathione.

The human multidrug resistance protein (MRP1) confers resistance of cells to a number of different cytostatic drugs and functions as an export pump for glutathione S-conjugates, glucuronides and other amphiphilic anions. The present study details for the first time MRP1-mediated ATP-dependent transp...

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Main Authors: Barnouin, K., Leier, I., Jedlitschky, G., Pourtier-Manzanedo, A., König, J., Lehmann, W. D., Keppler, D.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1998
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151220/
https://ncbi.nlm.nih.gov/pubmed/9460989
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