A regulatory role for porphobilinogen deaminase (PBGD) in delta-aminolaevulinic acid (delta-ALA)-induced photosensitization?

As an initial approach to optimize delta-aminolaevulinic acid (delta-ALA)-induced photosensitization of tumours, we examined the response of three enzymes of the haem biosynthetic pathway: delta-ALA dehydratase, porphobilinogen deaminase (PBGD) and ferrochelatase. Only PBGD activity displayed a time...

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Main Authors: Gibson, S. L., Cupriks, D. J., Havens, J. J., Nguyen, M. L., Hilf, R.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1998
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151216/
https://ncbi.nlm.nih.gov/pubmed/9460994
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