Cross-Protection against Lethal H5N1 Challenge in Ferrets with an Adjuvanted Pandemic Influenza Vaccine

BACKGROUND: Unprecedented spread between birds and mammals of highly pathogenic avian influenza viruses (HPAI) of the H5N1 subtype has resulted in hundreds of human infections with a high fatality rate. This has highlighted the urgent need for the development of H5N1 vaccines that can be produced ra...

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Main Authors: Baras, Benoît, Stittelaar, Koert J., Simon, James H., Thoolen, Robert J. M. M., Mossman, Sally P., Pistoor, Frank H. M., van Amerongen, Geert, Wettendorff, Martine A., Hanon, Emmanuel, Osterhaus, Albert D. M. E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151135/
https://ncbi.nlm.nih.gov/pubmed/18167560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001401
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