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Chemical basis of glycine riboswitch cooperativity

The glycine binding riboswitch forms a unique tandem aptamer structure that binds glycine cooperatively. We employed nucleotide analog interference mapping (NAIM) and mutagenesis to explore the chemical basis of glycine riboswitch cooperativity. Based on the interference pattern, at least two sites...

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Bibliographic Details
Main Authors: Kwon, Miyun, Strobel, Scott A.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151043/
https://ncbi.nlm.nih.gov/pubmed/18042658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.771608
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