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Chemical basis of glycine riboswitch cooperativity

The glycine binding riboswitch forms a unique tandem aptamer structure that binds glycine cooperatively. We employed nucleotide analog interference mapping (NAIM) and mutagenesis to explore the chemical basis of glycine riboswitch cooperativity. Based on the interference pattern, at least two sites...

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Autors principals: Kwon, Miyun, Strobel, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151043/
https://ncbi.nlm.nih.gov/pubmed/18042658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.771608
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