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Degradation of hypomodified tRNA(i)(Met) in vivo involves RNA-dependent ATPase activity of the DExH helicase Mtr4p
Effective turnover of many incorrectly processed RNAs in yeast, including hypomodified tRNA(i) (Met), requires the TRAMP complex, which appends a short poly(A) tail to RNA designated for decay. The poly(A) tail stimulates degradation by the exosome. The TRAMP complex contains the poly(A) polymerase...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151029/ https://ncbi.nlm.nih.gov/pubmed/18000032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.808608 |
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