A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands

MicroRNAs (miRNAs) are ∼22-nucleotide RNAs that are processed from characteristic precursor hairpins and pair to sites in messages of protein-coding genes to direct post-transcriptional repression. Here, we report that the miRNA iab-4 locus in the Drosophila Hox cluster is transcribed convergently f...

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Detalhes bibliográficos
Main Authors: Stark, Alexander, Bushati, Natascha, Jan, Calvin H., Kheradpour, Pouya, Hodges, Emily, Brennecke, Julius, Bartel, David P., Cohen, Stephen M., Kellis, Manolis
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151017/
https://ncbi.nlm.nih.gov/pubmed/18172160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1613108
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