Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5′ to 3′ and 3′ to 5′

Eitemau Tebyg

• mRNAs containing the histone 3′ stem–loop are degraded primarily by decapping mediated by oligouridylation of the 3′ end
  gan: Su, Wei, et al.
  Cyhoeddwyd: (2013)
• The histone mRNA 3' end is required for localization of histone mRNA to polyribosomes.
  gan: Sun, J, et al.
  Cyhoeddwyd: (1992)
• Deep sequencing shows multiple oligouridylations are required for 3′ to 5′ degradation of histone mRNAs on polyribosomes
  gan: Slevin, Michael K., et al.
  Cyhoeddwyd: (2014)
• Determining degradation intermediates and the pathway of 3’ to 5’ degradation of histone mRNA using high-throughput sequencing
  gan: Holmquist, Christopher E., et al.
  Cyhoeddwyd: (2018)
• Histone mRNA concentrations are regulated at the level of transcription and mRNA degradation.
  gan: Sittman, D B, et al.
  Cyhoeddwyd: (1983)