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Endogenous antioxidant enzymes and glutathione S-transferase in protection of mesothelioma cells against hydrogen peroxide and epirubicin toxicity.

We have previously shown that cultured malignant mesothelioma cells contain elevated manganese superoxide dismutase (MnSOD) mRNA levels and activities compared with non-malignant mesothelial cells. As many cytotoxic drugs generate both superoxide and hydrogen peroxide, we assessed the relative signi...

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Main Authors: Kinnula, K., Linnainmaa, K., Raivio, K. O., Kinnula, V. L.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150125/
https://ncbi.nlm.nih.gov/pubmed/9569045
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