Endogenous antioxidant enzymes and glutathione S-transferase in protection of mesothelioma cells against hydrogen peroxide and epirubicin toxicity.

We have previously shown that cultured malignant mesothelioma cells contain elevated manganese superoxide dismutase (MnSOD) mRNA levels and activities compared with non-malignant mesothelial cells. As many cytotoxic drugs generate both superoxide and hydrogen peroxide, we assessed the relative signi...

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Bibliographic Details
Main Authors: Kinnula, K., Linnainmaa, K., Raivio, K. O., Kinnula, V. L.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1998
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150125/
https://ncbi.nlm.nih.gov/pubmed/9569045
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