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Oncogenic potential of bifunctional bioreductive drugs.

Potential oncogenicity must be a factor of concern in the design and development of novel bioreductive drugs. In the present studies, the cytotoxicity and oncogenic transforming potential of a series of heterocyclic mono-N-oxides, designed to be used as bioreductive drugs, were examined using the mo...

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Bibliographic Details
Main Authors: Hei, T. K., Liu, S. X., Hall, E. J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150017/
https://ncbi.nlm.nih.gov/pubmed/8763847
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